By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Values are generally displayed in milligram per kilo soil (dry weight).

Inherently biodegradable, fulfilling specific criteria; Inherently biodegradable, not fulfilling specific criteria, Under test conditions no biodegradation observed. The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Otherwise data is displayed as provided by the registrant(s). EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Release to the environment of this substance can occur from industrial use: manufacturing of the substance. This section summarises the values related to long term toxicity to fish from all registered dossiers for the substance. See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term: The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. For more information on total tonnage band calculation please consult the Data submission manual.

Values are generally displayed in milligrams per kilogram (dry weight). We will send it to your Email address shortly. For example CLH index numbers, CN numbers, deleted CAS numbers, etc. Within the context of REACH, impurities are unintended constituents present in a substance as manufactured. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre. Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. This section displays the values related to acute toxicity from all registered dossiers for the substance.

Your information is safe with us. Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance. Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory. Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C. Alcohol: An organic compound in which the hydroxyl functional group (–OH) is bound to a saturated carbon atom. This section summarises the values related to phototransformation in water from all registered dossiers for the substance. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population).

Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. Short–term toxicity to aquatic invertebrates, Long–term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria, Toxicity to aquatic plants other than algae, Endocrine disruptor testing in aquatic vertebrates - in vivo, Toxicity to terrestrial macroorganisms except arthropods. Note: Registrants can also select ‘other’ as the type of density. Room temperature in continental US; may vary elsewhere. Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. The results of matching substance classifications are displayed in percentages of the total number of notifications.

Solubility in mg/100g standard fat at 20°C provides substance information on the substance solubility in standard fat in milligram per 100 gram at a temperature of 20°C. Precautionary measures and guidance on safe use concern the use and handling of the specific substance, not of the presence of the substance in other articles or mixtures.

No data available: testing technically not feasible. Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. Thirdly the display of data is prioritised by unit.

Applicant’s summary and conclusion – Interpretation of results (dermal). ECHA has no public registered data indicating whether or into which articles the substance might have been processed. This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. Applicant’s summary and conclusion – Interpretation of results provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options: Note: Registrants can also select ‘other’ as picklist option for describing the biodegradation values of the substance in water. If you have any comments or suggestions, please contact ECHA using our contact form. Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C. Data is generally displayed in milligrams per kilogram bodyweight per day.Prioritization by test species: See ‘Summary effect on fertility oral route’. 1), Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.1), Self-heating substances and mixtures (Cat.2), Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.2), Substances or mixtures which in contact with water releases flammable gases (Cat.3), Substances and mixtures which in contact with water emit flammable gases, Contact with water liberates highly flammable gases, Spontaneously flammable in air (pyrophoric), Projection hazard but not a mass explosion hazard (Div. Therefore the quality of these names may be variable. Log Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. BOD5 provides substance information on the substance’s BOD5 values displayed in O2 (milli)gram per gram test material. The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. This section summarises the values related to hydrolysis from all registered dossiers for the substance. Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C. If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. EC10 / LC10 or NOEC for freshwater invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater invertebrates or the no observed effect concentration for freshwater invertebrates. SMILES is the acronym for Simplified Molecular Input Line Entry Specification, a chemical notation system used to represent a molecular structure by a linear string of symbols. Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. This section summarises the values related to Henry’s law constant (H) from all registered dossiers for the substance.

Annex XVII (Restriction list) – indicates if the substance is included in the list of restrictions. Due to the quantity of information and the number of chemicals, the Brief Profile is automatically generated based on the information available and is not manually verified. Provides information if the substance has been identified by one of the following previous EU chemicals regulatory frameworks: The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under CLP (Classification Labelling and Packaging) Regulation. Registrants can choose from the following picklist endpoint conclusions: Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system.
If so, the data provided is not processed for the Brief Profile. The availability of additional data beyond the five results displayed is indicated by (…) icon. Registrants can provide data for one or more of the following picklist options: Note: Registrants can also select ‘other’ as the solvent. If more than one type of substance is registered, both types will be displayed. This section summarises the density values from all registered dossiers for the substance. The following properties have been highlighted as critical: The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process).

The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years.


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